Our Stress IV contains some natural occurring calming agents which work by increasing the neurochemical in the brain GABA. Since GABA is an amino acid which acts as a neurotransmitter in the central nervous system. GABA’s natural function is to reduce the activity of the neurons to which it binds. It inhibits nerve transmission in the brain, calming nervous activity.
Magnesium is natural muscle relaxer and calming agent by increasing GABA. It has been shown in some studies to be as powerful sedation agent, compared to some narcotics, without the side effects and risk of drug addiction, Further one does not risk respiratory depression. (1)
Most studies compare taking magnesium pills which appears not be as effective as the intravenous form of magnesium. These studies have mixed results unlike the studies by intravenous administration which appear more supportive of the mental health effects.
Overall there are some mixed results in scientific studies which show benefit as adjunct for preoperative sedation in anesthesia though long term sedation or benefit is not known.(2) Overall we will need further study , but many psychiatrist feel magnesium is helpful for anxiety and stress disorders. (3)
Comparison of the analgesic effects of intravenous
magnesium sulfate infusion versus intrathecal fentanyl in patients with
severe pre-eclampsia undergoing caesarean section
Ahmed Said Elgebaly1, Ahmed Ali Eldabaa1, Ahmed Ali Abd ELhafez1, Manal Mostafa Abdalla2
1 Anaesthesia and SICU, Faculty of Medicine, Tanta University, Egypt
2 Department of Obstetrics and Gynecology , Faculty of Medicine, Tanta University, Egypt
2. Education | April 2011
Magnesium—Essentials for Anesthesiologists
Susanne Herroeder, M.D.; Marianne E. Schönherr, M.D., D.E.S.A.; Stefan G. De Hert, M.D., Ph.D.; Markus W. Hollmann, M.D., Ph.D., D.E.A.A.
3. Psychiatry Advisor July 22, 2014
Magnesium: An Essential Supplement for Psychiatric Patients
Barbara Bartlik, MD, Vanessa Bijlani, MD